In a high-scoring clash, the San Francisco 49ers topped the Arizona Cardinals 51-28 in Week 3 of the 2026 season. With both teams looking to establish early momentum, the outcome was pivotal for positioning as they navigate the challenges of the season. Brock Purdy led the charge for the 49ers with an impressive 283 passing yards, while Christian McCaffrey showcased his versatility on the ground with 114 rushing yards. Although Carson Beck delivered a standout performance for the Cardinals, tossing four touchdown passes, it wasn't enough to keep pace with San Francisco's dynamic offense. Trey McBride also made a mark for Arizona, racking up 102 receiving yards in a strong effort. Defensively, the 49ers made crucial plays that shifted the momentum of the game, including an interception by Darrick Forrest that stifled a potential scoring drive for Arizona. The turning point came midway through the second quarter when San Francisco's defense forced a turnover and quickly capitalized with a touchdown, extending their lead and setting the tone for the remainder of the contest. Ultimately, it was a comprehensive team effort that allowed the 49ers to outlast the Cardinals and secure the victory.