In a tightly contested matchup, the Detroit Lions outlasted the Buffalo Bills with a final score of 21-13, securing their second win of the season. The stakes were high in this Week 2 showdown, as both teams aimed to establish momentum early in the 2026 campaign. Malik Willis starred for the Lions, throwing for 226 yards and three touchdowns, showcasing his ability to lead the offense effectively. De'Von Achane contributed significantly with 88 receiving yards, helping to stretch the field and keep the Bills' defense on their toes. Meanwhile, Jeremiyah Love of the Bills made a strong impact on the ground, rushing for 127 yards, but it wasn't enough to tip the scales in Buffalo's favor. The defensive effort from the Lions played a crucial role in their victory. Calais Campbell led the charge with three total tackles, while Derick Hall recorded a pivotal sack that disrupted the Bills' rhythm. The turning point came in the fourth quarter when Jacob Rodriguez intercepted a pass, but the Lions' defense held firm, ultimately sealing the game and handing the Bills their first loss of the season.