In a commanding performance, the Arizona Cardinals topped the Los Angeles Rams 38-7 in Week 6 of the 2026 season. The victory not only solidifies Arizona's position in the playoff hunt but also serves as a strong statement against a division rival. Joe Milton shone for the Cardinals, throwing for 252 yards and three touchdowns, showcasing his ability to lead the offense effectively. Trey McBride was his top target, racking up 100 receiving yards and providing a consistent threat downfield. Meanwhile, the Rams struggled to find any rhythm, with Matthew Stafford's 34 rushing yards being the highlight of their lackluster offensive showing. Defensively, the Cardinals were relentless, with Josh Sweat contributing two sacks and Cody Simon snagging an interception to halt any momentum the Rams tried to build. The turning point came in the second quarter when Arizona's defense forced a turnover, allowing Milton to capitalize with a quick touchdown pass that shifted the game's momentum decisively in their favor. With Devin Moore leading the defense with three total tackles, the Cardinals' unit proved to be a formidable force throughout the contest.