In a commanding performance, the San Francisco 49ers defeated the Seattle Seahawks 42-7 in Week 5 of the 2026 season. This victory not only boosts the 49ers' confidence but also solidifies their position in the playoff hunt, showcasing their dominance in the highly competitive NFC West. Brock Purdy led the charge for San Francisco, throwing for 271 yards and two touchdowns, effectively guiding his offense throughout the game. Chase Brown contributed significantly on the ground with 98 rushing yards, while George Kittle was a reliable target, racking up 89 receiving yards. Together, they formed a potent offensive trio that overwhelmed the Seahawks' defense. On the defensive side, the 49ers were relentless, highlighted by Nick Bosa's three sacks, which disrupted Seattle's rhythm and put constant pressure on their quarterback. Renardo Green's eight tackles ensured that San Francisco maintained control of the field, while Ashtyn Davis's interception showcased their ability to capitalize on mistakes. The turning point came early in the second quarter when the 49ers scored back-to-back touchdowns, effectively sealing the game and leaving the Seahawks struggling to recover.