In a thrilling opening to the 2028 season, the San Francisco 49ers topped the Seattle Seahawks with a final score of 56-45. Both teams came into this matchup looking to establish dominance early, but it was the 49ers who came away victorious in a high-scoring affair that showcased their offensive fireworks. Leading the charge for San Francisco was quarterback Tyler Shough, who threw for an impressive 381 yards and five touchdowns, demonstrating precision and poise under pressure. On the receiving end, Jeff Caldwell also shone brightly, racking up 127 receiving yards and contributing significantly to the team’s aerial assault. Meanwhile, the Seahawks found a star of their own in Breece Hall, who rushed for 214 yards, but ultimately, it wasn't enough to overcome the 49ers' explosive offense. Defensively, the 49ers made crucial plays to secure their victory, highlighted by Damon Wilson Jr.'s 2.5 sacks that consistently disrupted Seattle's rhythm. Evan Johnson led the team with five total tackles, providing a steady presence throughout the game. The turning point came late in the third quarter when Shough connected with Caldwell for a touchdown that extended the lead to two scores, putting the 49ers in the driver’s seat and setting the tone for the remainder of the contest.