In a high-octane showdown, the San Francisco 49ers topped the Seattle Seahawks 42-27 in Week 5 of the 2026 season, solidifying their position as contenders in the NFC West. With playoff implications looming, both teams entered the game eager for a crucial victory, but it was the 49ers who came out on top with a commanding offensive performance. Leading the charge for the 49ers was Brock Purdy, who threw for three touchdowns and showcased his ability to command the field. Christian McCaffrey was a force on the ground, racking up 137 rushing yards and keeping the Seahawks' defense on its heels. Meanwhile, Seattle's Sam Darnold put up impressive numbers with 294 passing yards, but the Seahawks struggled to keep pace with San Francisco’s dynamic scoring. Defensively, the 49ers made key plays that shifted the momentum in their favor. Nick Bosa tallied a sack that disrupted Seattle's rhythm, while Malik Mustapha's interception proved pivotal in stalling a potential Seahawks comeback. The turning point came in the second quarter when San Francisco scored back-to-back touchdowns, creating a gap that Seattle couldn't close, ultimately sealing their fate in this exciting divisional clash.