In a commanding performance, the San Francisco 49ers defeated the Miami Dolphins 45-10 in Week 2 of the 2026 season. With this victory, the 49ers solidify their early-season momentum, showcasing their dominance on both sides of the ball. Brock Purdy was the standout star for San Francisco, throwing for an impressive 337 yards and four touchdowns, demonstrating his ability to effectively lead the offense. Meanwhile, Mike Evans was a key target, racking up 132 receiving yards, while Christian McCaffrey contributed on the ground with 63 rushing yards. The combination of Purdy's precision and Evans' playmaking made it a challenging day for the Dolphins' defense. Defensively, the 49ers were equally effective, with Dre Greenlaw registering a sack and Jack Jones securing an interception to disrupt Miami’s offensive rhythm. The turning point came early in the second quarter when Jones intercepted a pass, setting up Purdy’s third touchdown throw and giving San Francisco a commanding lead that they maintained throughout the game. The Dolphins struggled to recover from that momentum swing, ultimately leading to their defeat.