The Arizona Cardinals topped the Seattle Seahawks 38-21 in a thrilling Week 2 matchup of the 2026 season, solidifying their position as a team to watch this year. With both teams looking to establish early momentum, the stakes were high, but the Cardinals proved to be the stronger side on their home turf. Arizona's quarterback Jacoby Brissett was nothing short of spectacular, throwing for an impressive 514 yards and four touchdowns. His connection with tight end Trey McBride was particularly lethal, as McBride racked up 245 receiving yards, showcasing his ability to stretch the field and make big plays when it mattered most. The Cardinals' offense was firing on all cylinders, consistently finding ways to exploit the Seahawks' defense. Defensively, the Cardinals were able to apply pressure, with Andrew Billings recording two sacks that disrupted Seattle's rhythm. The turning point came in the second half when Brissett's touchdown pass to McBride extended Arizona's lead, forcing the Seahawks to play catch-up. Despite a strong defensive effort from Seattle, including two interceptions from Ameer Speed, it wasn’t enough to overcome the Cardinals' explosive offensive performance.