In a decisive Week 4 matchup, the Denver Broncos topped the San Francisco 49ers with a final score of 28-17, solidifying their position in the early part of the 2026 season. With both teams vying for playoff positioning, the Broncos delivered a strong performance, showcasing their offensive strengths and tactical execution. Leading the charge for Denver was quarterback Bo Nix, who threw for an impressive 299 yards, connecting efficiently with his receivers. Courtland Sutton emerged as the standout target, racking up 112 receiving yards and providing crucial plays downfield. Meanwhile, Jaydon Blue added a solid ground game with 72 rushing yards, complementing the aerial attack and keeping the 49ers' defense on their heels. Defensively, the Broncos made a significant impact, with Jonathon Cooper recording two sacks that disrupted San Francisco's rhythm. The turning point came in the second half when Cooper's pressure forced a critical turnover, allowing the Broncos to capitalize and extend their lead. Despite strong tackling efforts from Renardo Green of the 49ers, who led the game with 11 total tackles, Denver's balanced offensive approach ultimately proved too much for San Francisco to overcome.