The Buffalo Bills showcased their dominance in Week 16, defeating the Tennessee Titans decisively with a final score of 38-7. With playoff implications on the line, the Bills solidified their position in the postseason race, while the Titans struggled to find their footing in a tough matchup. Josh Allen led the charge for Buffalo, throwing for 250 yards and keeping the offense firing on all cylinders. Mecole Hardman emerged as his favorite target, racking up 115 receiving yards and contributing significantly to the Bills' high-scoring output. The Titans' Cam Ward managed to throw one touchdown but was largely contained throughout the game, leaving Tennessee's offense looking for answers. Defensively, the Bills made key plays that swung the momentum in their favor. Dee Alford's interception put a halt to a promising Titans drive, while the Buffalo defense consistently pressured Ward, limiting his effectiveness. The turning point came early in the second half when the Bills scored back-to-back touchdowns to stretch their lead, putting the game out of reach for Tennessee.