The Seattle Seahawks put on a dominant performance against the San Francisco 49ers, winning decisively with a final score of 54-20 in Week 5 of the 2026 season. This victory solidifies the Seahawks’ position as a formidable contender in the league, showcasing their offensive firepower and defensive resilience. Jalen Milroe was the star of the show, throwing for an impressive 477 yards and five touchdowns, leading Seattle's high-octane offense. He connected frequently with Jaxon Smith-Njigba, who racked up a staggering 196 receiving yards, creating mismatches all afternoon. Jadarian Price added to the offensive onslaught with 80 rushing yards, helping to keep the 49ers' defense on their heels. On the defensive side, the Seahawks were relentless, with Leo Chenal making eight total tackles to anchor the unit. DeMarcus Lawrence contributed significantly with 1.5 sacks, applying pressure on the 49ers' quarterback throughout the game. The turning point came when Devon Witherspoon intercepted a pass, halting a San Francisco drive and shifting momentum firmly in Seattle’s favor.