In a dominant performance, the San Francisco 49ers topped the Seattle Seahawks 45-6 in Week 5 of the 2026 season. With this victory, the 49ers not only solidified their standing in the NFC but also sent a strong message to the rest of the league about their championship aspirations. Brock Purdy led the charge for San Francisco, throwing for 289 yards and three touchdowns, connecting efficiently with his targets throughout the game. Christian McCaffrey complemented the aerial attack with a strong ground game, rushing for 93 yards, while Ricky Pearsall emerged as a standout receiver with 114 yards. The 49ers' offense operated with precision, consistently finding ways to break through the Seahawks' defense. The 49ers' defense also played a crucial role, stifling the Seahawks' offensive efforts and forcing them into tough situations. Although CJ West managed to snag half a sack, it was the relentless pressure and coverage that turned the tide in favor of San Francisco. The game's turning point came early in the second quarter when the 49ers forced a turnover, allowing them to extend their lead and control the pace for the remainder of the match.