In a dominant display, the Buffalo Bills topped the Denver Broncos 42-10 in Week 16 of the 2026 season, solidifying their playoff position. With this victory, the Bills showcased their offensive prowess while the Broncos struggled to keep pace, marking a crucial moment in the late-season push. Josh Allen was the standout performer for Buffalo, throwing for 132 yards and three touchdowns, effectively leading the charge against Denver's defense. Khalil Shakir added to the aerial assault with 49 receiving yards, while J.K. Dobbins managed to put up a respectable 107 rushing yards for the Broncos, albeit in a losing effort. Defensively, the Bills were relentless, with Davison Igbinosun recording eight total tackles and Greg Rousseau contributing 1.5 sacks. The turning point came when Maxwell Hairston intercepted a pass, shifting momentum firmly in Buffalo's favor and allowing their offense to capitalize on the Broncos' mistakes throughout the game.