The Philadelphia Eagles triumphed over the San Francisco 49ers with a final score of 38-22 in a critical Week 16 matchup that solidified their playoff positioning. With both teams vying for postseason glory, the Eagles' powerful performance at home proved decisive as they overwhelmed the 49ers. Jalen Hurts was the standout performer for Philadelphia, throwing for an impressive 360 yards and four touchdowns, showcasing his dual-threat ability. Ahmad Hardy added a strong ground game with 112 rushing yards, while DeVonta Smith was a reliable target, racking up 119 receiving yards. Together, they orchestrated an offensive display that kept the 49ers on their heels throughout the game. Defensively, Philadelphia made its mark with Jalen Carter leading the charge, recording two sacks that disrupted San Francisco's rhythm. The turning point came late in the second quarter when Hurts connected with Smith for a 60-yard touchdown, swinging momentum firmly in favor of the Eagles. Despite a strong effort from Upton Stout and the 49ers' defense, they could not contain the Eagles' explosive offense, sealing the victory for Philadelphia.