In a thrilling Week 6 matchup, the Arizona Cardinals narrowly defeated the San Francisco 49ers with a final score of 28-24. Both teams entered the contest eager to solidify their standings in the competitive NFC, and the stakes were high as they battled for playoff positioning. Quarterback Justin Fields led the Cardinals' offense with a solid performance, throwing for 208 yards, while Brock Purdy of the 49ers threw two touchdown passes but fell short in the end. On the ground, Calvin Monroe shined for San Francisco, racking up 135 rushing yards and providing a consistent threat, but it was Marvin Harrison Jr. who stole the spotlight for Arizona, posting 100 receiving yards and proving to be a key playmaker. Defensively, the game was marked by standout performances, including Colt Berry's five tackles for the Cardinals, which helped stifle the 49ers' momentum. The turning point came late in the fourth quarter when Malik Mustapha intercepted a crucial pass from Purdy, allowing Arizona to secure the victory and maintain their edge in the division. Despite Nick Bosa's two sacks for San Francisco, the Cardinals’ defense ultimately made the plays that mattered most in this hard-fought contest.