The San Francisco 49ers topped the Arizona Cardinals 38-16 in a decisive Week 3 matchup that showcased their offensive firepower. With this victory, the 49ers improved their standing in the competitive NFC West, while the Cardinals struggled to find their footing early in the season. Brock Purdy was the standout performer for San Francisco, throwing for 321 yards and three touchdowns, effectively leading the 49ers' offense. His ability to connect with receivers downfield opened up the game, while the rushing attack complemented the aerial assault, keeping the Cardinals' defense on its heels. On the other side, Jeremiyah Love led the ground game for Arizona with 68 rushing yards, and Marvin Harrison Jr. provided a bright spot with 150 receiving yards, but it wasn't enough to keep pace with the 49ers. Defensively, San Francisco made crucial plays to stifle Arizona’s momentum, particularly with Jimmie Ward's interception, which shifted the game's dynamics. The 49ers’ defense consistently pressured the Cardinals, limiting their scoring opportunities and forcing key mistakes. The turning point came in the second quarter when Purdy's sharp passing led to a quick touchdown drive, putting the 49ers ahead and establishing a lead that they would not relinquish.