In a dominant display, the San Francisco 49ers topped the Miami Dolphins 45-10 in Week 2 of the 2026 season. The victory solidifies the 49ers' early claim to supremacy in the league, showcasing both offensive firepower and defensive prowess. Brock Purdy led the charge for San Francisco, throwing for 300 yards and three touchdowns, showcasing his ability to connect with his receivers. Ricky Pearsall was a standout target, racking up 107 receiving yards, while Christian McCaffrey added a solid ground game with 102 rushing yards. The 49ers' offense was relentless, maintaining pressure on the Dolphins' defense throughout the game. Defensively, the 49ers were equally impressive, with Nick Bosa contributing significantly by recording 1.5 sacks. While the Dolphins struggled to find their rhythm, Jordyn Brooks' 10 tackles stood out as a lone bright spot for Miami. The turning point came early in the second quarter when Purdy threw a long touchdown to Pearsall, shifting the momentum firmly in San Francisco's favor and allowing them to pull away decisively.