In a thrilling Week 2 matchup of the 2026 season, the Miami Dolphins topped the San Francisco 49ers with a decisive 49-28 victory. The win was crucial for Miami as they look to establish themselves early in the season while the 49ers aimed to bounce back from an opening-week loss. Offensively, the Dolphins were propelled by an explosive performance from De'Von Achane, who racked up an astonishing 344 rushing yards, showcasing his speed and agility. Meanwhile, Brock Purdy of the 49ers threw for 312 yards and four touchdowns, keeping San Francisco competitive throughout the game. Ricky Pearsall also made an impact for the 49ers, leading the receiving corps with 109 yards. The Dolphins' defense played a pivotal role, with Kenneth Grant recording 1.5 sacks and Jacob Rodriguez grabbing an interception, creating key turnovers that shifted momentum. The turning point came in the second quarter when Miami's defense stifled a 49ers drive, allowing Achane to capitalize with a long touchdown run shortly after, giving the Dolphins a lead they would not relinquish.