The Los Angeles Rams cruised to a commanding 45-17 victory over the Arizona Cardinals in Week 10 of the 2026 season. With playoff implications hanging in the balance, the Rams showcased their offensive firepower, solidifying their position in the postseason race. Matthew Stafford was the standout performer, throwing for 361 yards and four touchdown passes, leading a dynamic Rams offense. Kyren Williams contributed significantly on the ground, racking up 102 rushing yards, while Puka Nacua emerged as a key target with 136 receiving yards, making big plays that kept the Cardinals’ defense on its heels throughout the game. Defensively, the Rams stifled the Cardinals' offense, forcing key turnovers and limiting scoring opportunities. The turning point came in the second quarter when a crucial interception set up a quick touchdown drive, allowing Los Angeles to stretch their lead to 24-10, effectively putting the game out of reach for Arizona. Despite a solid effort from Ekow Boye-Doe, who led the Cardinals with nine tackles, it wasn't enough to slow down the relentless Rams attack.