In a stunning display of dominance, the Los Angeles Chargers crushed the San Francisco 49ers with a final score of 100-0 in Week 15 of the 2026 season. This matchup showcased the Chargers' offensive firepower and solidified their position as a formidable contender in the league. The 49ers struggled to find their footing, leaving them with a disheartening defeat. Chargers quarterback Justin Herbert put on a historic performance, throwing for an astonishing 899 yards and 13 touchdowns, showcasing his elite skills and leadership. Brenen Thompson was the standout receiver, accumulating 621 yards and finding the end zone multiple times, giving the Chargers an explosive aerial attack. The team's offensive line provided solid protection, allowing Herbert to execute his game plan flawlessly. On the defensive side, the Chargers were equally impressive, with Tre Hawkins III leading the way with five total tackles and three interceptions, halting any chance of a 49ers comeback. Tuli Tuipulotu made his presence felt with three sacks, consistently pressuring the quarterback and disrupting San Francisco's offense. The game’s turning point came early when the Chargers scored quickly and often, leaving the 49ers unable to recover from the onslaught.