In a dominant performance, the Indianapolis Colts defeated the New York Giants 44-3 in Week 12 of the 2026 season. With this win, the Colts solidified their position as a formidable force in the league, showcasing their offensive prowess and defensive strength against a struggling Giants team. Quarterback Anthony Richardson Sr led the charge for Indianapolis, throwing for 188 yards and three touchdowns, effectively spreading the ball around and keeping the Giants' defense on their heels. Running back Jonathan Taylor was unstoppable on the ground, racking up an impressive 202 rushing yards, while Alec Pierce contributed significantly in the passing game with 89 receiving yards. The Colts' offense consistently exploited mismatches and maintained momentum throughout the game. Defensively, the Colts were relentless, spearheaded by DeForest Buckner, who recorded two sacks, and CJ Allen, who intercepted two passes, providing critical turnovers that shifted the game's momentum. JT Tuimoloau's four total tackles helped stifle any potential Giants drives. The turning point came early in the second quarter when the Colts scored back-to-back touchdowns, effectively sealing the game and leaving the Giants with little chance to recover.