In a dominant display, the San Francisco 49ers shut out the Arizona Cardinals with a final score of 28-0, solidifying their position in the early part of the 2026 season. This Week 3 matchup proved crucial for the 49ers as they look to establish themselves as a force in the NFC. Brock Purdy led the way for San Francisco, throwing for 143 yards and three touchdown passes, showcasing his efficiency and poise in the pocket. Meanwhile, Christian McCaffrey added 57 rushing yards, while Mike Evans emerged as a key target, racking up 89 receiving yards. The offensive unit clicked seamlessly, finding the end zone multiple times to secure the victory. Defensively, the 49ers were relentless, with standout performances from Fred Warner, who tallied four total tackles, and Osa Odighizuwa, who recorded two sacks. The turning point came when Renardo Green intercepted a pass in the first half, setting the tone for a defensive onslaught that left the Cardinals unable to respond. San Francisco's defense not only held Arizona scoreless but also generated crucial turnovers, sealing a statement win.