In a dominant display, the Arizona Cardinals topped the San Francisco 49ers with a final score of 43-6, solidifying their playoff aspirations in Week 14 of the 2027 season. The Cardinals showcased their offensive firepower, while the 49ers struggled to find their footing throughout the game. Quarterback Jalen Hurts led the charge for Arizona, throwing for 231 yards and four touchdowns, demonstrating precision and poise in the pocket. Ja'Kobi Lane emerged as his favorite target, racking up 108 receiving yards and proving to be a constant threat downfield. Despite the 49ers' efforts, Jayden Daniels managed to rush for 90 yards, but it was not enough to mount a serious challenge against the Cardinals' high-flying offense. Defensively, Abdul Carter was a standout for Arizona, making six tackles and registering four sacks, putting relentless pressure on the 49ers' offense. The turning point came in the second quarter when Carter's sack led to a critical turnover, allowing the Cardinals to capitalize and extend their lead. With a stunning performance on both sides of the ball, Arizona effectively neutralized San Francisco, sealing an impressive victory.