In a commanding performance, the Los Angeles Rams topped the San Francisco 49ers with a final score of 28-7 in Week 1 of the 2026 season. The Rams came into the season looking to assert their dominance in the division, and this game set the tone for their campaign. Matthew Stafford shone for the Rams, throwing for 315 yards and two touchdowns, effectively leading the offense throughout the contest. Puka Nacua was a standout target, racking up an impressive 153 receiving yards, showcasing his ability to stretch the field. Meanwhile, Christian McCaffrey led the ground game for San Francisco with 87 rushing yards, but it wasn’t enough to keep pace with the Rams’ aerial assault. Defensively, the Rams were relentless, with Myles Garrett making a significant impact by recording 2.5 sacks. Nate Landman contributed with a solid five total tackles, helping to stifle the 49ers’ attempts to gain momentum. The turning point came in the second quarter when Kam Curl intercepted a pass, setting up another Rams touchdown and solidifying their control over the game.