In a tightly contested battle, the San Francisco 49ers topped the Seattle Seahawks 27-20 in Week 5 of the 2026 season. The victory was crucial for the 49ers as they aimed to solidify their position in the playoff race, while the Seahawks sought to bounce back from previous setbacks. Brock Purdy led the charge for San Francisco with a remarkable 386 passing yards, showcasing his ability to connect with his receivers. George Pickens was the standout target, amassing 178 receiving yards, while Javonte Williams added a solid ground presence with 78 rushing yards. Despite Sam Darnold's two touchdown passes for Seattle, it wasn't enough to turn the tide in their favor. Defensively, the 49ers made key plays that ultimately swayed the game. Jaylon Johnson's interception provided a crucial moment, stifling a potential scoring drive for Seattle. The game changed when the 49ers capitalized on that turnover, turning the momentum and maintaining their lead down the stretch, showcasing the importance of defensive execution in tight matchups.