In a commanding performance, the Arizona Cardinals crushed the Detroit Lions 44-0 in Week 5 of the 2026 season. This lopsided victory solidifies the Cardinals' position as a formidable contender, while the Lions will need to regroup after a disappointing outing. Quarterback Josh Allen was the star of the show, throwing for 304 yards and an impressive six touchdown passes. Allen also contributed on the ground, adding 47 rushing yards, while Antonio Williams lit up the scoreboard with 199 receiving yards, showcasing the Cardinals' explosive offensive capabilities. Defensively, the Cardinals dominated, led by Jalen Thompson's seven total tackles and Renardo Green's interception, which helped stifle any potential Lions' drive. The game turned decisively in the second quarter when Allen threw three touchdown passes within a span of just over five minutes, effectively putting the game out of reach for Detroit.