The San Francisco 49ers topped the Dallas Cowboys with a commanding 39-18 victory in Week 10 of the 2026 season. With playoff implications on the line, the 49ers showcased their dominance, solidifying their position in the postseason race while the Cowboys struggled to keep pace. Quarterback Mac Jones led the way for San Francisco, throwing for 238 yards and effectively managing the game. Kyle Juszczyk provided a strong ground presence, rushing for 102 yards, while Brandon Aiyuk was a reliable target, hauling in 73 receiving yards. The 49ers’ offensive efficiency was key in establishing a significant lead early on. Defensively, the 49ers were impactful, with Alfred Collins recording a sack that disrupted the Cowboys’ rhythm. The game’s turning point came in the second quarter when San Francisco scored consecutive touchdowns, pushing their lead to 24-6 and forcing Dallas to play from behind. With Jaishawn Barham leading the Cowboys' defense with 11 total tackles, it wasn't enough to turn the tide against a relentless 49ers attack.