In a decisive Week 3 matchup, the San Francisco 49ers topped the Arizona Cardinals 36-19, solidifying their position in the early season standings. With both teams looking to establish momentum, the 49ers managed to outlast the Cardinals, showcasing a well-rounded performance on both sides of the ball. Joe Flacco led the charge for San Francisco, throwing for three touchdown passes, while Derrick Henry contributed a solid ground game with 75 rushing yards. Trevor Lawrence put up a valiant effort for Arizona with 282 passing yards and Jeremiyah Love emerged as a key target, racking up 110 receiving yards. Despite their offensive output, the Cardinals struggled to keep pace with the 49ers' efficiency. Defensively, the 49ers made crucial plays that shifted the momentum in their favor. Vita Vea recorded a sack that pressured Lawrence at key moments, while Jihaad Campbell's interception helped swing the tide in the second half. The combination of timely turnovers and strong tackling, led by Kelvin Joseph's four total tackles for Arizona, ensured that San Francisco maintained control and ultimately secured the victory.