In a pivotal Week 4 matchup, the Detroit Lions defeated the San Francisco 49ers by a score of 23-13, solidifying their position in the playoff race early in the 2028 season. The Lions were looking to make a statement against a formidable opponent, and they did just that with a strong all-around performance. Lions quarterback Darian Mensah led the charge, throwing for 305 yards and one touchdown, while Jahmyr Gibbs added a solid 70 rushing yards to keep the 49ers' defense honest. DJ Moore was the standout receiver, racking up an impressive 136 yards, showcasing his big-play ability and providing Mensah with a reliable target throughout the game. Defensively, the Lions managed to stifle the 49ers' offense, forcing them into tough situations and limiting their big plays. The turning point came in the second half when Detroit's defense tightened up, allowing only a single touchdown drive while maintaining pressure on San Francisco. Despite a strong effort from Fred Warner, who recorded 13 tackles, the 49ers couldn't find their rhythm, ultimately leading to their defeat.