In a commanding display, the Los Angeles Chargers topped the Buffalo Bills 38-17 in Week 3 of the 2026 season, showcasing their offensive prowess and solidifying their position early in the campaign. With this victory, the Chargers improve their record, while the Bills will need to regroup as they face challenges ahead. Chargers quarterback Justin Herbert was the standout performer, throwing for 355 yards and four touchdowns, effectively leading his team throughout the matchup. Complementing his efforts, running back Omarion Hampton rushed for 104 yards, while wide receiver Quentin Johnston had a remarkable game with 222 receiving yards, making it a tough night for the Bills' secondary. Defensively, the Chargers made crucial plays to stifle the Bills' momentum. Teair Tart registered a sack, while Derwin James Jr. intercepted a key pass, shifting the game's momentum in favor of Los Angeles. The turning point came when James' interception led to yet another touchdown drive for the Chargers, effectively sealing the game and leaving Buffalo struggling to respond.