In a decisive Week 4 matchup, the San Francisco 49ers topped the Detroit Lions with a final score of 29-12, solidifying their place in the playoff race. The 49ers showcased their dominance on both sides of the ball, leveraging their home-field advantage to thwart the Lions' attempts at a comeback. Dante Moore led the charge for San Francisco, throwing for an impressive 306 yards while spreading the ball effectively across his receiving corps. De'Zhaun Stribling was a key target, racking up 104 receiving yards, while the 49ers' ground game was anchored by Christian McCaffrey, who contributed 49 rushing yards. Despite Vince Young's two touchdown passes for Detroit, the Lions struggled to keep pace on offense throughout the game. Defensively, the 49ers made a significant impact, with Nick Bosa’s standout performance including three sacks that disrupted the Lions' rhythm. The turning point came in the second quarter when Bosa's relentless pressure led to a critical turnover, allowing San Francisco to extend their lead and ultimately control the game. With a solid defensive showing, the 49ers effectively neutralized Detroit's offensive efforts, ensuring their victory.