In a commanding display of offensive prowess, the San Francisco 49ers toppled the Denver Broncos with a final score of 58-28. This Week 4 matchup of the 2026 season showcased the 49ers' dominance as they solidified their position in the league with a resounding victory over their opponents. Brock Purdy led the charge for San Francisco, throwing for five touchdowns, while Christian McCaffrey put on a show with an astounding 322 rushing yards. De'Zhaun Stribling contributed to the aerial assault with 91 receiving yards, helping to keep the Broncos on their heels throughout the contest. Bo Nix managed to keep pace for Denver with 200 passing yards, but it was clear that the Broncos struggled to match the 49ers' offensive firepower. Defensively, the 49ers were relentless, with Nick Bosa racking up 5 total tackles and an impressive 3.5 sacks. Fred Warner’s interception added to the defensive highlight reel, further stifling any hopes of a Denver comeback. The turning point came in the second quarter when San Francisco scored three consecutive touchdowns, effectively putting the game out of reach and leaving the Broncos scrambling to respond.