The Miami Dolphins topped the San Francisco 49ers with a commanding 38-22 victory in Week 2 of the 2026 season. With both teams looking to establish themselves early in the season, the Dolphins proved they are a force to be reckoned with in the AFC. Cade Klubnik was the standout performer for Miami, throwing for 235 yards and three touchdowns, showcasing his ability to lead the offense effectively. De'Von Achane also had a stellar game, rushing for 157 yards, while Caleb Douglas added to the aerial attack with 95 receiving yards, helping to keep the 49ers’ defense on its heels throughout the contest. Defensively, Miami made key plays to secure the win, with VJ Payne recording an interception that halted a promising San Francisco drive. Although the 49ers' Renardo Green created pressure with a sack, it was the Dolphins' ability to force turnovers and maintain control of the pace that ultimately determined the outcome of the game. Miami's defense, coupled with its explosive offense, turned the tide early and paved the way for a dominant performance.