In a thrilling season opener, the Arizona Cardinals defeated the Los Angeles Chargers 24-17, kicking off the 2026 season with a strong performance. The game showcased a battle of wills as both teams aimed for an early statement win, but it was the Cardinals who emerged victorious on the road. Jacoby Brissett led the way for Arizona, throwing for 272 yards and delivering key plays throughout the contest. Jeremiyah Love made a significant impact on the ground, racking up 107 rushing yards, while Michael Wilson was a standout in the receiving game, finishing with 139 yards and a touchdown. The Cardinals' offense found its rhythm and made the most of their opportunities, ultimately securing the win. Defensively, the Cardinals were bolstered by a critical performance from Mack Wilson Sr., who recorded a sack that shifted momentum in Arizona's favor. Khalil Mack of the Chargers was a force on defense with nine total tackles, but it was the Cardinals' ability to make key stops and capitalize on turnovers that turned the tide. The turning point came late in the game when Arizona's defense held firm, denying the Chargers a chance to tie the game in the final minutes.