In a decisive Week 3 matchup, the San Francisco 49ers topped the Arizona Cardinals 35-14, solidifying their position in the early 2026 season. With both teams vying for dominance in the NFC West, this victory gives the 49ers a crucial leg up in the division race. Brock Purdy was the star of the show, throwing for an impressive 371 yards and four touchdowns, showcasing his ability to command the offense. Christian McCaffrey contributed significantly on the ground with 60 rushing yards, while Trey McBride led the Cardinals' efforts in receiving with 171 yards, though it wasn't enough to keep pace with San Francisco's explosive attack. Defensively, the 49ers made key plays that shifted momentum in their favor. Fred Warner recorded three tackles and snagged an interception, while Romello Height added 1.5 sacks, putting pressure on the Cardinals' offense throughout the game. The turning point came when San Francisco's defense forced a turnover, allowing Purdy to extend the lead and put the game out of reach for Arizona.