In a decisive Week 2 clash, the San Francisco 49ers topped the Miami Dolphins with a commanding 42-17 victory. The win puts the 49ers in a strong position early in the 2026 season, showcasing their offensive firepower and solidifying their status as a contender. Brock Purdy was the standout performer for San Francisco, throwing for 297 yards and five touchdown passes, effectively leading the 49ers' offensive onslaught. Christian McCaffrey also made his mark, racking up 107 receiving yards, providing a reliable target for Purdy and keeping the Dolphins' defense on their heels. De'Von Achane led Miami's ground game with 53 rushing yards but struggled to find the end zone. Defensively, the 49ers were relentless, highlighted by Nate Hobbs' four total tackles and Nick Bosa's sack, which disrupted Miami's rhythm. The turning point came midway through the second quarter when Purdy connected on a quick touchdown pass, extending the lead to 21-10. From there, the 49ers maintained control, forcing Miami to play catch-up, ultimately sealing the game with their dominant performance.