In a thrilling Week 3 matchup of the 2026 season, the Arizona Cardinals topped the San Francisco 49ers with a final score of 33-24. The stakes were high as both teams sought to solidify their position in a competitive conference, but it was the Cardinals who emerged victorious, showcasing their offensive firepower. Leading the charge for Arizona was quarterback Jacoby Brissett, who threw for 281 yards and three touchdowns, showcasing precision and poise throughout the game. Running back Jeremiyah Love added 87 rushing yards, complementing Brissett's aerial attack, while Kendrick Bourne was a standout receiver with 92 yards, making critical catches to keep drives alive. Defensively, the Cardinals made significant plays that shifted momentum in their favor. Walter Nolen III recorded two sacks, pressuring the 49ers' offense and disrupting their rhythm, while Garrett Williams contributed with a pivotal interception that halted a San Francisco scoring opportunity. The Cardinals' ability to capitalize on key defensive moments ultimately secured their victory in this hard-fought contest.