In a decisive Week 2 matchup, the Buffalo Bills topped the Detroit Lions with a commanding 42-21 victory, showcasing their offensive prowess and setting the tone for the 2026 season. Both teams entered the game looking for momentum, but it was the Bills who seized control early and never looked back. Josh Allen was the star of the show, throwing for 334 yards and four touchdowns, effectively dismantling the Lions' secondary. D.J. Turner also emerged as a key target, racking up 103 receiving yards while helping to stretch the field and keep the Lions' defense on its heels. Jahmyr Gibbs did his best to keep Detroit competitive with a solid 106 rushing yards, but it was clear the Bills' offense was firing on all cylinders. Buffalo's defense played a critical role in securing the win, with C.J. Gardner-Johnson leading the way with four total tackles and Christian Benford contributing a sack to disrupt Detroit's rhythm. The game's turning point came early in the second half when the Bills' defense forced a crucial turnover, allowing Allen to capitalize with another touchdown drive, effectively sealing the victory. The Lions struggled to recover from that momentum shift, leaving the Bills in firm control as they celebrated a strong start to their season.