Cardinals at 49ers

Franchise Hub Beat · 12d ago

In a thrilling shootout, the Arizona Cardinals narrowly defeated the San Francisco 49ers 59-52 in Week 4 of the 2027 season. This high-stakes matchup showcased both teams’ offensive firepower, but it was the Cardinals who emerged victorious, keeping their playoff hopes alive.

Josh Allen was the star of the night for Arizona, throwing for an impressive 414 yards and four touchdowns, while DeMario Douglas added a strong ground game with 92 rushing yards. The Cardinals’ offense was relentless, consistently finding ways to exploit the 49ers' defense and keeping the pressure on throughout the game. Meanwhile, Christian Watson shone for San Francisco, racking up 109 receiving yards to help keep his team competitive.

Defensively, the Cardinals made critical plays that shaped the outcome, with Azeez Al-Shaair securing two key interceptions that halted potential scoring drives for the 49ers. The turning point came late in the fourth quarter when Al-Shaair's second pick led to a touchdown that put Arizona ahead for good. Despite a valiant effort from Patrick Surtain II and Aaron Donald, San Francisco's defense couldn't contain the Cardinals when it mattered most.