In a commanding performance, the Buffalo Bills triumphed over the Denver Broncos with a final score of 38 to 11 in Week 16 of the 2026 season. With playoff positioning on the line, this victory solidifies the Bills' standing as a formidable contender in the postseason race. Josh Allen was the standout for Buffalo, throwing for 259 yards and two touchdowns, showcasing his ability to lead the offense effectively. DJ Moore was his favorite target, racking up 90 receiving yards, while James Cook III contributed significantly on the ground with 68 rushing yards. Together, they powered the Bills' offensive onslaught that overwhelmed the Broncos. Defensively, the Bills maintained a strong presence, with Greg Rousseau recording a sack that disrupted Denver's rhythm. Although Alex Singleton of the Broncos led the game with 11 tackles, it was Buffalo's defensive unit that consistently applied pressure, forcing the Broncos into unfavorable situations. The turning point came early in the second half when Rousseau’s sack shifted momentum, leading to a crucial turnover that the Bills capitalized on to extend their lead.