In a thrilling Week 6 matchup of the 2027 season, the San Francisco 49ers topped the Arizona Cardinals with a final score of 31-20, solidifying their position in the playoff race. With both teams looking to gain momentum, the stakes were high as they fought for crucial conference standings. Offensively, Brock Purdy led the charge for the 49ers, throwing for two touchdowns and complementing his efforts with a strong performance from Christian McCaffrey, who rushed for 109 yards. Justin Fields kept the Cardinals competitive with his impressive 331 passing yards, with Trey Palmer emerging as his favorite target, racking up 118 receiving yards. Despite the loss, Arizona's offense showcased resilience throughout the game. Defensively, the 49ers made critical plays that turned the tide in their favor. Renardo Green was a standout with eight total tackles, while Romello Height's 2.5 sacks put consistent pressure on Fields, disrupting the Cardinals' rhythm. The game's turning point came when Deommodore Lenoir snagged an interception, halting a potential scoring drive and allowing San Francisco to extend their lead.