In a commanding performance, the San Francisco 49ers topped the Miami Dolphins 42-21 in Week 2 of the 2026 season. With both teams looking to establish early momentum, the 49ers secured the victory, showcasing their offensive prowess and defensive strength. Brock Purdy led the charge for San Francisco, throwing for 326 yards and three touchdowns, proving to be a formidable presence behind center. His favorite target, Mike Evans, racked up 115 receiving yards, consistently finding openings in the Dolphins' secondary. Meanwhile, Malik Willis was the standout for Miami, rushing for 68 yards as he attempted to keep pace with the high-octane San Francisco offense. Defensively, the 49ers were relentless, with Malik Mustapha leading the team in tackles with six, and Dre Greenlaw contributing with a key sack. The turning point came in the second quarter when San Francisco's defense stifled a Dolphins drive, leading to a quick turnover that allowed Purdy to capitalize and extend their lead. This sequence shifted the momentum firmly in favor of the 49ers, paving the way for their decisive victory.