The Denver Broncos secured a commanding 41-28 victory over the San Francisco 49ers in Week 4 of the 2026 season. With playoff aspirations on the line, this matchup proved crucial for both teams, but it was Denver that ultimately emerged as the victor. Offensively, the Broncos were led by RJ Harvey, who rushed for 98 yards, providing a strong ground game that complemented the aerial attack. Quarterback play was highlighted by Courtland Sutton's standout performance, as he racked up 102 receiving yards and helped move the chains at key moments. Although San Francisco's Brock Purdy threw for an impressive 303 yards and three touchdowns, it wasn't enough to keep pace with Denver's scoring surge. Defensively, the Broncos managed to stifle the 49ers' rhythm when it mattered most. San Francisco's defense applied pressure, with DaQuan Jones recording a sack and Upton Stout intercepting a pass, but they struggled to contain Denver’s explosive offense. The game's turning point came in the third quarter when the Broncos scored two quick touchdowns, creating a gap the 49ers could not close, ultimately sealing Denver's victory.