In a dominant display, the San Francisco 49ers defeated the Seattle Seahawks 49-24 in Week 5 of the 2026 season. The victory not only solidifies the 49ers' position in the playoff hunt but also serves as a statement win against a division rival. Brock Purdy was the star of the night for San Francisco, throwing for an impressive 295 yards and three touchdowns. Christian McCaffrey contributed significantly on the ground with 95 rushing yards, while Ricky Pearsall emerged as a key target, racking up 111 receiving yards. The 49ers' offense operated efficiently, showcasing a balanced attack that kept the Seahawks on their heels. On the defensive side, San Francisco's Dre Greenlaw recorded a crucial sack, helping to disrupt Seattle's offensive rhythm. Despite the efforts of Julian Love, who tallied 12 tackles for the Seahawks, the 49ers' defense played a pivotal role in shaping the game’s outcome. The turning point came late in the second quarter when San Francisco's defense stifled a Seahawks drive, allowing the 49ers to extend their lead just before halftime.