In a dominant display, the San Francisco 49ers cruised to a 110-26 victory over the New York Jets in Week 10 of the 2028 season. With this win, the 49ers solidified their playoff positioning while the Jets faced a harsh reality check as they struggled to keep pace in the league. Tyler Shough was the star of the show for San Francisco, throwing an impressive eight touchdown passes while also leading the team in rushing with 34 yards. Despite the lopsided score, Drew Mestemaker of the Jets put up a valiant effort, racking up 483 passing yards and connecting with Duce Robinson for a remarkable 257 receiving yards, showcasing their offensive firepower even in defeat. Defensively, the 49ers made their mark with Hezekiah Masses intercepting three passes, effectively stifling any potential momentum for New York. The turning point came midway through the second quarter when Masses' first interception led to a quick touchdown, propelling San Francisco to a commanding lead that the Jets could never recover from. Nick Bosa's two sacks also highlighted the Jets' struggles to protect Mestemaker, further contributing to the 49ers' overwhelming victory.