In a commanding performance, the Los Angeles Chargers topped the San Francisco 49ers 33-0 in Week 15 of the 2026 season. With playoff implications on the line, the Chargers solidified their position in the postseason race, showcasing a dominant display on both sides of the ball. Quarterback Justin Herbert was the standout on offense, throwing for an impressive 438 yards and three touchdowns, effectively leading his team throughout the game. Brenen Thompson emerged as his top target, racking up 197 receiving yards, consistently finding ways to exploit the 49ers' secondary. Meanwhile, Christian McCaffrey led the 49ers' ground game with 64 rushing yards, but it wasn’t nearly enough to make an impact. Defensively, the Chargers were relentless, with Khalil Mack contributing a sack and Cam Hart making a pivotal impact with two interceptions. The turning point came in the second quarter when Hart picked off a pass, setting up Herbert’s second touchdown throw and effectively putting the game out of reach for San Francisco. Overall, the Chargers' defense stifled the 49ers, preventing them from finding any offensive rhythm and preserving the shutout.