In a decisive Week 16 matchup, the Buffalo Bills topped the Denver Broncos with a final score of 45-29, solidifying their playoff aspirations as the regular season draws to a close. The Bills’ balanced attack was too much for the Broncos to handle, showcasing their offensive prowess throughout the contest. Josh Allen led the Bills with a strong performance, throwing for 268 yards while James Cook III dominated on the ground with 108 rushing yards. Dalton Kincaid was a reliable target, amassing 116 receiving yards and contributing significantly to the Bills' scoring efforts. Meanwhile, Bo Nix kept the Broncos competitive with two passing touchdowns, but it wasn't enough to keep pace with Buffalo's offensive explosion. Buffalo's defense made crucial stops, highlighted by Greg Rousseau's sack that shifted momentum in the first half. The turning point came when the Bills forced a turnover that allowed them to extend their lead, leaving the Broncos struggling to catch up. Despite a commendable effort from Denver's Riley Moss, who tallied seven tackles, the Bills' relentless offense ultimately proved too formidable.