In a thrilling Week 3 matchup, the Arizona Cardinals narrowly defeated the San Francisco 49ers by a final score of 21-20. Both teams entered the game looking to establish momentum early in the season, but it was the Cardinals who came out on top in a tightly contested battle. Brock Purdy was the standout for the 49ers, throwing for 306 yards and two touchdowns, showcasing his ability to lead the offense effectively. Christian McCaffrey added 89 rushing yards, while Mike Evans was a key target, racking up 97 receiving yards. Despite their efforts, the 49ers fell just short of securing a win. Defensively, the Cardinals made crucial plays that shifted the game's momentum. Garrett Williams led the defense with 11 total tackles, while Walter Nolen III contributed with 1.5 sacks, helping to apply pressure on Purdy throughout the game. Sean Murphy-Bunting's interception proved pivotal, sealing the victory for Arizona and ensuring they held off the 49ers in the final moments.