In a commanding performance, the Arizona Cardinals topped the San Francisco 49ers 42-24 in Week 14 of the 2028 season. This victory keeps the Cardinals firmly in the playoff hunt, showcasing their offensive firepower against a divisional rival. Leading the charge for Arizona was quarterback Jaron-Keawe Sagapolutele, who threw for an impressive 423 yards and three touchdowns, while Marvin Harrison Jr. emerged as his favorite target with a staggering 228 receiving yards. The Cardinals' offense was relentless, consistently moving the ball and capitalizing on scoring opportunities, which ultimately set the tone for the game. Defensively, Will Johnson was a standout for the Cardinals, recording seven tackles and an interception, which proved crucial in shifting momentum. The game's turning point came in the second quarter when Johnson's interception halted a promising drive from the 49ers, allowing the Cardinals to extend their lead and maintain control for the rest of the game.