In a thrilling matchup in Week 10 of the 2027 season, the San Francisco 49ers topped the Tennessee Titans with a final score of 45-23. The victory keeps the 49ers firmly in playoff contention, while the Titans look to regroup as the season progresses. Brock Purdy showcased his passing prowess for San Francisco, throwing for an impressive 309 yards and three touchdowns. Ricky Pearsall emerged as a key target, racking up 138 receiving yards, while the 49ers' offense efficiently moved the ball and converted crucial drives into points. On the ground, Josh Walton of the Titans put up a strong performance with 190 rushing yards, but it wasn’t enough to keep pace with San Francisco's explosive attack. Defensively, the 49ers made their presence felt, with Theo Davis recording a sack and Marques Sigle snagging an interception to disrupt Tennessee's rhythm. The game’s turning point came in the second quarter when Purdy connected with Pearsall for a touchdown that shifted momentum definitively in favor of the 49ers. Although Alontae Taylor led the Titans with four tackles, the San Francisco defense ultimately limited Tennessee’s scoring opportunities, sealing the victory with a strong performance.